Products

ANESTHETICS, GENERAL

Anti-parkinson drugs, dopaminergic agents

*under development

ANTI‑PARKINSON DRUGS, DOPAMINERGIC AGENTS

* under development

MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS

This medicine is used as an adjunct to general anesthesia to facilitate tracheal intubation, to relax skeletal muscles during surgery or controlled ventilation, and to facilitate mechanical ventilation of patients in the intensive care unit.

Analgesics, Opioids

VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN B6 AND B12

This medicine is used for treatment of haematologic and neurologic symptoms caused by continuous deficiency of vitamins B1, B6 and B12 in adults and children over 12 years.

VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN B6 AND B12

This medicine is used for treatment of haematologic and neurologic symptoms caused by continuous deficiency of vitamins B1, B6 and B12 in adults and children over 12 years.

POSTERIOR PITUITARY LOBE HORMONES

*under development

MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS

This medicine is used:
- to relax muscles during operations on adults and children over 1 month of age, including heart surgery
- to help insert a tube into the windpipe (tracheal intubation), if a person needs help to breathe
- to relax the muscles of adults in intensive care.

ANTIIFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS

This medicine is used for symptomatic treatment of acute pain of moderate to severe intensity, when oral administration is not appropriate such as post-operative pain, renal colic and low back pain.

HYPNOTICS AND SEDATIVES

This medicine belongs to provide sedation (a state of calm, drowsiness or sleep) for adult patients in hospital intensive care settings.

PSYCHOLEPTICS, ANTIPSYCHOTICS

The product is indicated for:
- Prevention and treatment of post-operative nausea and vomiting in adults and, as second line, in children (2 to 11 years) and adolescents (12 to 18 years).
- Prevention of nausea and vomiting induced by morphine derivatives during post-operative patient controlled analgesia (PCA) in adults.

ANESTHETICS, GENERAL

This medicine belongs to one of a group of medicines called anaesthetic agents, which are used to put you to sleep during an operation.
This medicine can be given:
- alone or in combination with other anaesthetic agents;
- as a pain relief/anaesthesia in emergency situations;
- can be used for supplementing regional or local anaesthesia.

ANESTHETICS, GENERAL

This medicine is used:
- as a narcotic analgesic supplement in general or regional anaesthesia;
- in combination with a neuroleptic (e.g. droperidol) in the technique of neuroleptanalgesia;
- for the induction of anaesthesia, and as an adjuvant in the maintenance of general and regional anaesthesia;
- as an anaesthetic agent with oxygen in high-risk patients undergoing surgery.

ANALGESIC, OPIOID

*under development

ANALGESICS, OPIOIDS

*under development

Analgesics, Opioids

Diuretic

Therapeutic indications
Indicated when no adequate diuresis is achieved with oral administration of furosemide or when oral use is not possible:
- oedemas and/or ascites secondary to cardiac or hepatic disorders
- oedemas secondary to renal disorders
- oedemas secondary to burns
- pulmonary oedema (e.g. in acute heart failure)
- supportive measure in cerebral oedema
- oliguria secondary to gestosis, if necessary after correction of a hypovolaemic state (NB: oedemas and/or hypertension in cases of gestosis are not an indication)
- hypertensive crisis (in addition to other therapeutic measures)

DIURETICS, SULFONAMIDES, PLAIN

* under development

ANALGESIC, OPIOID

This medicine is used for the treatment of severe pain.

X-RAY CONTRAST MEDIA, IODINATED

*under development

Cardiac simulants

Therapeutic indications
Indicated for the short-term treatment of acutely decompensated severe chronic heart failure (ADHF) in situations where conventional therapy is not sufficient, and in cases where inotropic support is considered appropriate.

*Under development

BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS, I.V. SOLUTION ADDITIVES

Additional Strength: 500 mg/ml (WHO prequalified) 2 ml and 10 ml

This medicine is used for:
- Treatment and prevention of hypomagnesaemia in clinical conditions which may be associated with magnesium deficiency such as prolonged diarrhoea, diabetes mellitus, malabsorption syndromes, alcoholism, cirrhosis of the liver, during pregnancy and breast-feeding period, in case of renal diseases with polyuria, as well as during administration of “loop” diuretics;
- Prevention and treatment of hypomagnesaemia in patients on total parenteral nutrition;
- Seizure prevention (e. g. epilepsy, uraemia in patients with nephropathy);
- Prevention and treatment of pre-eclampsia and eclampsia in late pregnancy toxemia, as well as to stop spontaneous abortion and preterm labour;
- Treatment of the early stages of arterial hypertension as antispasmodic medicine;
- Prevention of arrhythmias (e. g. torsade de pointes-type arrhythmias, arrhythmias with signs of hypokalemia).

ANALGESICS, OTHER ANALGESICS AND ANTIPYRETICS

This medicine is used for treatment of severe acute or chronic pain. Fever not responding to other treatment.

HYPNOTICS AND SEDATIVES

This medicine is a short-acting hypnotic with the following indications for use:

Adults
• CONSCIOUS SEDATION with or without local anaesthesia before or during diagnostic or therapeutic procedures
• ANAESTHESIA
- Premedication before the induction of anaesthesia
- Induction of anaesthesia
- As a sedative component in maintenance of anaesthesia
• SEDATION IN THE INTENSIVE CARE UNIT

Children
• CONSCIOUS SEDATION with or without local anaesthesia before or during diagnostic or therapeutic procedures
• ANAESTHESIA
- Premedication before the induction of anaesthesia
• SEDATION IN THE INTENSIVE CARE UNIT

MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS

Mivacurium is a highly selective, short-acting, non-depolarising neuromuscular blocking agent with a fast recovery profile.
Mivacurium is indicated as an adjunct to general anaesthesia to relax skeletal muscles and to facilitate tracheal intubation and mechanical ventilation in adults, children and infants 2 months and over.

ANALGESIC, OPIOID

This medicine is used for treatment of severe pain conditions which can be adequately managed only with opioid analgesics. Myocardial infarction, acute pulmonary oedema.

Analgesics, Opioids

ANALGESIC, OPIOID

This medicine is used for the relief of severe pain. It is also used to treat breathlessness caused by fluid in the lungs and as a pre-medication before operations.

ANALGESICS, OTHER

* under development

OTHER NERVOUS SYSTEM DRUGS, PARASYMPATHOMIMETICS

This medicine is indicated for:
- myasthenia gravis.
- reversal of the neuromuscular blockade produced by non-depolarising neuromuscular blockers.
- paralytic ileus.
- management of postoperative urinary retention.

CARDIAC STIMULANTS

Therapeutic indications
Recommended for use as an emergency measure in the restoration of blood pressure in cases of acute hypotension.

Antiemetics and Antinauseants

*under development

ANALGESIC, OPIOID

This medicine is used for:
- the treatment of moderate to severe pain in patients with cancer and postoperative pain;
- the treatment of severe pain requiring the use of a strong opioid.

Analgesics, Opioids

ANTIEMETICS AND ANTINAUSEANTS

Therapeutic indications

The medicine is indicated in adults for:
­- the prevention of acute nausea and vomiting associated with highly emetogenic cancer chemotherapy;
­- the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy.

The medicine is indicated in paediatric patients 1 month of age and older for:
­- the prevention of acute nausea and vomiting associated with highly emetogenic cancer chemotherapy and prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy.

*under development

Drugs for peptic ulcer and gastro-oesophageal reflux disease (Gord)

Therapeutic indications

- Reflux oesophagitis.
- Gastric and duodenal ulcer.
- Zollinger-Ellison-Syndrome and other pathological hypersecretory conditions.

*Under development

PSYCHOANALEPTICS, PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS

This medicine is used for treatment of dizziness of central origin and its related symptoms.
Treatment of myoclonus caused by cerebral cortex damage in combination with other anti-myoclonic medicines.

VITAMINS, OTHER PLAIN VITAMIN PREPARATIONS

This medicine is indicated for:
- Vitamin B6 deficiency (including in patients on dialysis);
- sideroblastic anaemia (congenital, secondary, drug- and toxin-induced and other);
- metabolic disorders (increased excretion of xanthurenic acid, primary cystathioninuria, primary hyperoxaluria, primary homocystinuria);
- isoniazid-induced neuropathy; - pyridoxine-dependent seizures in infants;
- premenstrual syndrome.

ANESTHETICS, GENERAL

*under development

Anti-dementia drug

*under development

MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS

This medicine is indicated in adult and paediatric patients (from term neonates to adolescents [0 to <18 years]) as an adjunct to general anaesthesia to facilitate tracheal intubation during routine sequence induction and to provide skeletal muscle relaxation during surgery. In adults rocuronium bromide is also indicated to facilitate tracheal intubation during rapid sequence induction and as an adjunct in the intensive care unit (ICU) to facilitate intubation and mechanical ventilation.

ANESTHETICS, LOCAL

* under development

ANTIEMETICS AND ANTINAUSEANTS

Belladonna alkaloids, semisynthetic, quaternary ammonium compounds

Therapeutic indications
Acute spasm of the gastrointestinal tract, biliary tract, pancreas and urogenital tract.
As antispasmodic agent in radiology in different diagnostic procedures where spasm may be a problem (e.g. gastroduodenal endoscopy).

BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS, I.V. SOLUTION ADDITIVES

This medicine is used for dissolution or dilution of parenteral drugs. For the wounds, mucous membrane and eyes irrigation.

Other nervous system drugs

Treatment of narcolepsy with cataplexy in adult patients.

OTHER NERVOUS SYSTEM DRUGS

* under development

ANESTHETICS, GENERAL

*under development

ANALGESIC, OPIOID

This medicine is used for treatment of moderate to severe pain.

ANALGESIC, OPIOID

This medicine is used relieve severe pain in the case of injuries, fractures of bones, burns, miocardial infarction, acute pancreatitis, renal, biliary and intestinal colic, in the case of malignant tumour, as well as after surgery.
To relieve labour pain and to accelerate labour in the case of cervical dysfunction, when epidural anaesthesia is impossible and childbirth is predictable not earlier than after two hours.
For premedication before surgery.

ANTIHYPERTENSIVES

Therapeutic indications
Hypertensive emergencies (e.g. a critical rise in blood pressure), severe and very severe forms of hypertensive disease, hypertension resistant to treatment.
Controlled lowering of blood pressure in hypertensive patients during and/or after surgery.

ALL OTHER NON-THERAPEUTIC PRODUCTS

This medicine is used for dissolution or dilution of parenteral drugs. Vehicle for administration of compatible drug and electrolyte concentrate,
observing that the osmolarity of whole solution corresponds to 0.85-0.9 % of osmolarity of sodium chloride solution.