Products

Title
Alfentanil injection
Strength 0.5 mg/ml
Volume 1 ml, 2 ml, 10 ml
ATC code N01AH02

ANESTHETICS, GENERAL

Apomorphine hydrochloride hemihydrate injection*
Strength 5 mg/ml
ATC code N04BC07

Anti-parkinson drugs, dopaminergic agents

*under development

Apomorphine injection*
Strength 5 mg/ml
Volume 10 ml
ATC code N04BC07

ANTI‑PARKINSON DRUGS, DOPAMINERGIC AGENTS

* under development

Atracurium besilate injection
Strength 10 mg/ml
Volume 2.5 ml, 5 ml
ATC code M03AC04

MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS

This medicine is used as an adjunct to general anesthesia to facilitate tracheal intubation, to relax skeletal muscles during surgery or controlled ventilation, and to facilitate mechanical ventilation of patients in the intensive care unit.

Buprenorphine transdermal patches*
Strength 5 μg/h, 10 μg/h, 20 μg/h
ATC code N02AE01

Analgesics, Opioids

B-vitamins complex injection
Strength 50 mg / 50 mg / 0.5 mg / 10 mg/ml
Volume 2 ml
ATC code A11DB

VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN B6 AND B12

This medicine is used for treatment of haematologic and neurologic symptoms caused by continuous deficiency of vitamins B1, B6 and B12 in adults and children over 12 years.

B-vitamins complex tablets*
Volume 100 mg
ATC code A11DB

VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN B6 AND B12

This medicine is used for treatment of haematologic and neurologic symptoms caused by continuous deficiency of vitamins B1, B6 and B12 in adults and children over 12 years.

Carbetocin injection*
Strength 0.1 mg/ml
Volume 1 ml
ATC code H01BB03

POSTERIOR PITUITARY LOBE HORMONES

*under development

Cisatracurium injection
Strength 2 mg/ml
Volume 2.5 ml, 5 ml, 10 ml
ATC code M03AC11

MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS

This medicine is used:
- to relax muscles during operations on adults and children over 1 month of age, including heart surgery
- to help insert a tube into the windpipe (tracheal intubation), if a person needs help to breathe
- to relax the muscles of adults in intensive care.

Dexketoprofen injection
Strength 25 mg/ml
Volume 2 ml
ATC code M01AE17

ANTIIFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS

This medicine is used for symptomatic treatment of acute pain of moderate to severe intensity, when oral administration is not appropriate such as post-operative pain, renal colic and low back pain.

Dexmedetomidine injection
Strength 100 µg/ml
Volume 2 ml, 4 ml, 10 ml
ATC code N05CM18

HYPNOTICS AND SEDATIVES

This medicine belongs to provide sedation (a state of calm, drowsiness or sleep) for adult patients in hospital intensive care settings.

Droperidol injection
Strength 1.25 mg/ml, 2.5 mg/ml
Volume 1 ml
ATC code N05AD08

PSYCHOLEPTICS, ANTIPSYCHOTICS

The product is indicated for:
- Prevention and treatment of post-operative nausea and vomiting in adults and, as second line, in children (2 to 11 years) and adolescents (12 to 18 years).
- Prevention of nausea and vomiting induced by morphine derivatives during post-operative patient controlled analgesia (PCA) in adults.

Esketamine injection
Strength 5 mg/ml, 25 mg/ml
Volume 2 ml, 5 ml, 10 ml
ATC code N01AX14

ANESTHETICS, GENERAL

This medicine belongs to one of a group of medicines called anaesthetic agents, which are used to put you to sleep during an operation.
This medicine can be given:
- alone or in combination with other anaesthetic agents;
- as a pain relief/anaesthesia in emergency situations;
- can be used for supplementing regional or local anaesthesia.

Fentanyl injection
Strength 0.05 mg/ml
Volume 2 ml, 10 ml
ATC code N01AH01

ANESTHETICS, GENERAL

This medicine is used:
- as a narcotic analgesic supplement in general or regional anaesthesia;
- in combination with a neuroleptic (e.g. droperidol) in the technique of neuroleptanalgesia;
- for the induction of anaesthesia, and as an adjuvant in the maintenance of general and regional anaesthesia;
- as an anaesthetic agent with oxygen in high-risk patients undergoing surgery.

Fentanyl nasal spray*
Strength 50 µg/dose, 200 µg/dose
Volume 2.9 ml
ATC code N02AB03

ANALGESIC, OPIOID

*under development

Fentanyl sublingual tablets*
Strength 100 μg, 200 μg, 300 μg, 400 μg, 600 μg, 800 μg
Volume -
ATC code N02AB03

ANALGESICS, OPIOIDS

*under development

Fentanyl transdermal patches*
Strength 12.5 μg/h, 25 μg/h, 50 μg/h, 75 μg/h, 100 μg/h
ATC code N02AB03

Analgesics, Opioids

Furosemide injection
Strength 10 mg/ml
ATC code C03CA01

Diuretic

Therapeutic indications
Indicated when no adequate diuresis is achieved with oral administration of furosemide or when oral use is not possible:
- oedemas and/or ascites secondary to cardiac or hepatic disorders
- oedemas secondary to renal disorders
- oedemas secondary to burns
- pulmonary oedema (e.g. in acute heart failure)
- supportive measure in cerebral oedema
- oliguria secondary to gestosis, if necessary after correction of a hypovolaemic state (NB: oedemas and/or hypertension in cases of gestosis are not an indication)
- hypertensive crisis (in addition to other therapeutic measures)

Furosemide injection*
Strength 10 mg/ml
Volume 2 ml, 5 ml
ATC code C03CA01

DIURETICS, SULFONAMIDES, PLAIN

* under development

Hydromorphone hydrochloride injection
Strength 2 mg/ml, 10 mg/ml, 20 mg/ml, 50 mg/ml
Volume 1 ml
ATC code N02AA03

ANALGESIC, OPIOID

This medicine is used for the treatment of severe pain.

Iohexol*
Strength 300 mg/ml, 350 mg/ml
Volume 50 ml, 100 ml, 200 ml, 500 ml
ATC code V08AB02

X-RAY CONTRAST MEDIA, IODINATED

*under development

Levosimendan injection*
Strength 1.25 mg/ml, 2.5 mg/ml
Volume 1 ml
ATC code C01CX08

Cardiac simulants

Therapeutic indications
Indicated for the short-term treatment of acutely decompensated severe chronic heart failure (ADHF) in situations where conventional therapy is not sufficient, and in cases where inotropic support is considered appropriate.

*Under development

Magnesium sulfate heptahydrate injection/infusions
Strength 100 mg/ml*, 200 mg/ml*, 250 mg/ml
Volume 10 ml
ATC code B05XA05

BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS, I.V. SOLUTION ADDITIVES

Additional Strength: 500 mg/ml (WHO prequalified) 2 ml and 10 ml

This medicine is used for:
- Treatment and prevention of hypomagnesaemia in clinical conditions which may be associated with magnesium deficiency such as prolonged diarrhoea, diabetes mellitus, malabsorption syndromes, alcoholism, cirrhosis of the liver, during pregnancy and breast-feeding period, in case of renal diseases with polyuria, as well as during administration of “loop” diuretics;
- Prevention and treatment of hypomagnesaemia in patients on total parenteral nutrition;
- Seizure prevention (e. g. epilepsy, uraemia in patients with nephropathy);
- Prevention and treatment of pre-eclampsia and eclampsia in late pregnancy toxemia, as well as to stop spontaneous abortion and preterm labour;
- Treatment of the early stages of arterial hypertension as antispasmodic medicine;
- Prevention of arrhythmias (e. g. torsade de pointes-type arrhythmias, arrhythmias with signs of hypokalemia).

Metamizole sodium monohydrate injection
Strength 500 mg/ml
Volume 2 ml, 5 ml
ATC code N02BB02

ANALGESICS, OTHER ANALGESICS AND ANTIPYRETICS

This medicine is used for treatment of severe acute or chronic pain. Fever not responding to other treatment.

Midazolam injection
Strength 1 mg/ml, 5 mg/ml
Volume 1 ml, 3 ml, 5 ml, 10 ml
ATC code N05CD08

HYPNOTICS AND SEDATIVES

This medicine is a short-acting hypnotic with the following indications for use:

Adults
• CONSCIOUS SEDATION with or without local anaesthesia before or during diagnostic or therapeutic procedures
• ANAESTHESIA
- Premedication before the induction of anaesthesia
- Induction of anaesthesia
- As a sedative component in maintenance of anaesthesia
• SEDATION IN THE INTENSIVE CARE UNIT

Children
• CONSCIOUS SEDATION with or without local anaesthesia before or during diagnostic or therapeutic procedures
• ANAESTHESIA
- Premedication before the induction of anaesthesia
• SEDATION IN THE INTENSIVE CARE UNIT

Mivacurium injection
Strength 2 mg/ml
Volume 5 ml, 10 ml
ATC code M03AC10

MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS

Mivacurium is a highly selective, short-acting, non-depolarising neuromuscular blocking agent with a fast recovery profile.
Mivacurium is indicated as an adjunct to general anaesthesia to relax skeletal muscles and to facilitate tracheal intubation and mechanical ventilation in adults, children and infants 2 months and over.

Morphine hydrochloride injection
Strength 10 mg/ml, 20 mg/ml
Volume 1 ml, 5 ml, 10 ml
ATC code N02AA01

ANALGESIC, OPIOID

This medicine is used for treatment of severe pain conditions which can be adequately managed only with opioid analgesics. Myocardial infarction, acute pulmonary oedema.

Morphine prolonged release tablets*
Strength 10 mg, 30 mg, 60 mg, 100 mg
ATC code N02AA01

Analgesics, Opioids

Morphine sulfate injection (w/o preservatives)
Strength 2 mg/ml, 5 mg/ml, 10 mg/ml, 15 mg/ml, 30 mg/ml
Volume 1 ml
ATC code N02AA01

ANALGESIC, OPIOID

This medicine is used for the relief of severe pain. It is also used to treat breathlessness caused by fluid in the lungs and as a pre-medication before operations.

Nefopam hydrochloride  injection*
Strength 10 mg/ml
Volume 2 ml
ATC code N02BG06

ANALGESICS, OTHER

* under development

Neostigmine metilsulfate injection
Strength 0.5 mg/ml
Volume 1 ml
ATC code N07AA01

OTHER NERVOUS SYSTEM DRUGS, PARASYMPATHOMIMETICS

This medicine is indicated for:
- myasthenia gravis.
- reversal of the neuromuscular blockade produced by non-depolarising neuromuscular blockers.
- paralytic ileus.
- management of postoperative urinary retention.

Norepinephrine injection
Strength 1 mg/ml
Volume 1 ml, 2 ml, 4 ml, 5 ml, 8 ml, 10 ml, 25 ml
ATC code C01CA03

CARDIAC STIMULANTS

Therapeutic indications
Recommended for use as an emergency measure in the restoration of blood pressure in cases of acute hypotension.

Ondansetron injection*
Strength 2 mg/ml
ATC code A04AA01

Antiemetics and Antinauseants

*under development

Oxycodone hydrochloride injection/infusions
Strength 10 mg/ml, 50 mg/ml
Volume 1 ml, 2 ml
ATC code N02AA05

ANALGESIC, OPIOID

This medicine is used for:
- the treatment of moderate to severe pain in patients with cancer and postoperative pain;
- the treatment of severe pain requiring the use of a strong opioid.

Oxycodone prolonged release tablets*
Strength 5 mg, 10 mg, 20 mg, 40 mg, 80 mg
ATC code N02AA05

Analgesics, Opioids

Palonosetron injection*
Strength 0.05 mg/ml
Volume 5 ml
ATC code A04AA05

ANTIEMETICS AND ANTINAUSEANTS

Therapeutic indications

The medicine is indicated in adults for:
­- the prevention of acute nausea and vomiting associated with highly emetogenic cancer chemotherapy;
­- the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy.

The medicine is indicated in paediatric patients 1 month of age and older for:
­- the prevention of acute nausea and vomiting associated with highly emetogenic cancer chemotherapy and prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy.

*under development

Pantoprazole powder for solution for injection*
Strength 40 mg
Volume -
ATC code A02BC02

Drugs for peptic ulcer and gastro-oesophageal reflux disease (Gord)

Therapeutic indications

- Reflux oesophagitis.
- Gastric and duodenal ulcer.
- Zollinger-Ellison-Syndrome and other pathological hypersecretory conditions.

*Under development

Piracetam injection
Strength 200 mg/ml
Volume 5 ml, 10 ml
ATC code N06BX03

PSYCHOANALEPTICS, PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS

This medicine is used for treatment of dizziness of central origin and its related symptoms.
Treatment of myoclonus caused by cerebral cortex damage in combination with other anti-myoclonic medicines.

Pyridoxine hydrochloride injection
Strength 50 mg/ml
Volume 1 ml
ATC code A11HA02

VITAMINS, OTHER PLAIN VITAMIN PREPARATIONS

This medicine is indicated for:
- Vitamin B6 deficiency (including in patients on dialysis);
- sideroblastic anaemia (congenital, secondary, drug- and toxin-induced and other);
- metabolic disorders (increased excretion of xanthurenic acid, primary cystathioninuria, primary hyperoxaluria, primary homocystinuria);
- isoniazid-induced neuropathy; - pyridoxine-dependent seizures in infants;
- premenstrual syndrome.

Remifentanil powder for concentrate for solution for injection/infusion*
Volume 1 mg, 2 mg, 5 mg
ATC code N01AH06

ANESTHETICS, GENERAL

*under development

Rivastigmine transdermal patches*
Strength 4.6 μg/24h, 9.5 μg/24h, 13.3 μg/24h
ATC code N06DA03

Anti-dementia drug

*under development

Rocuronium bromide injection
Strength 10 mg/ml
Volume 5 ml
ATC code M03AC09

MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS

This medicine is indicated in adult and paediatric patients (from term neonates to adolescents [0 to <18 years]) as an adjunct to general anaesthesia to facilitate tracheal intubation during routine sequence induction and to provide skeletal muscle relaxation during surgery. In adults rocuronium bromide is also indicated to facilitate tracheal intubation during rapid sequence induction and as an adjunct in the intensive care unit (ICU) to facilitate intubation and mechanical ventilation.

Ropivacaine hydrochloride  injection*
Strength 2 mg/ml, 5 mg/ml, 7.5 mg/ml, 10 mg/ml
Volume 10 ml, 20 ml, 100 ml, 200 ml
ATC code N01BB09

ANESTHETICS, LOCAL

* under development

Scopolamine injection
Strength 20 mg/ml
Volume 1 ml
ATC code A03BB01

ANTIEMETICS AND ANTINAUSEANTS

Belladonna alkaloids, semisynthetic, quaternary ammonium compounds

Therapeutic indications
Acute spasm of the gastrointestinal tract, biliary tract, pancreas and urogenital tract.
As antispasmodic agent in radiology in different diagnostic procedures where spasm may be a problem (e.g. gastroduodenal endoscopy).

Sodium chloride injection
Strength 9 mg/ml
Volume 10 ml
ATC code B05XA03

BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS, I.V. SOLUTION ADDITIVES

This medicine is used for dissolution or dilution of parenteral drugs. For the wounds, mucous membrane and eyes irrigation.

Sodium oxybate oral solution
Strength 500 mg/ml
ATC code N07XX04

Other nervous system drugs

Treatment of narcolepsy with cataplexy in adult patients.

Sodium oxybate oral solution*
Strength 2.5 g/5 ml
Volume 180 ml
ATC code N07XX04

OTHER NERVOUS SYSTEM DRUGS

* under development

Sufentanil injection*
Strength 0.005 mg/ml, 0.05 mg/ml
Volume 2 ml, 5 ml, 10 ml
ATC code N01AH03

ANESTHETICS, GENERAL

*under development

Tramadol hydrochloride injection
Strength 50 mg/ml
Volume 1 ml, 2 ml
ATC code N02AX02

ANALGESIC, OPIOID

This medicine is used for treatment of moderate to severe pain.

Trimeperidine hydrochloride injection
Strength 20 mg/ml
Volume 1 ml
ATC code N02AX

ANALGESIC, OPIOID

This medicine is used relieve severe pain in the case of injuries, fractures of bones, burns, miocardial infarction, acute pancreatitis, renal, biliary and intestinal colic, in the case of malignant tumour, as well as after surgery.
To relieve labour pain and to accelerate labour in the case of cervical dysfunction, when epidural anaesthesia is impossible and childbirth is predictable not earlier than after two hours.
For premedication before surgery.

Urapidil injection
Strength 5 mg/ml
Volume 5 ml, 10 ml
ATC code C02CA06

ANTIHYPERTENSIVES

Therapeutic indications
Hypertensive emergencies (e.g. a critical rise in blood pressure), severe and very severe forms of hypertensive disease, hypertension resistant to treatment.
Controlled lowering of blood pressure in hypertensive patients during and/or after surgery.

Water for injection
Volume 10 ml
ATC code V07AB

ALL OTHER NON-THERAPEUTIC PRODUCTS

This medicine is used for dissolution or dilution of parenteral drugs. Vehicle for administration of compatible drug and electrolyte concentrate,
observing that the osmolarity of whole solution corresponds to 0.85-0.9 % of osmolarity of sodium chloride solution.