Central Nervous System

This group in Kalceks portfolio contains hypnotics, sedatives and psychoanaleptics/psychostimulants for usage in hospitals including premedication needs and intensive care units.

Products

Title
Alfentanil injection (generic of Rapifen®)
Strength 0.5 mg/ml, 5 mg/ml
Volume 1 ml, 2 ml, 10 ml
ATC code N01AH02

ANESTHETICS, GENERAL

Dexmedetomidine injection (generic of Dexdor®)
Strength 100 µg/ml
Volume 2 ml, 4 ml, 10 ml
ATC code N05CM18

HYPNOTICS AND SEDATIVES

This medicine belongs to provide sedation (a state of calm, drowsiness or sleep) for adult patients in hospital intensive care settings.

Droperidol injection*
Strength 1.25 mg/ml, 2.5 mg/ml
Volume 1 ml
ATC code N05AD08

PSYCHOLEPTICS, ANTIPSYCHOTICS

* under development

Esketamine injection  (generic of Ketanest® S)
Strength 5 mg/ml, 25 mg/ml
Volume 2 ml, 5 ml, 10 ml
ATC code N01AX14

ANESTHETICS, GENERAL

This medicine belongs to one of a group of medicines called anaesthetic agents, which are used to put you to sleep during an operation.
This medicine can be given:
- alone or in combination with other anaesthetic agents;
- as a pain relief/anaesthesia in emergency situations;
- can be used for supplementing regional or local anaesthesia.

Fentanyl injection
Strength 0.05 mg/ml
Volume 2 ml, 10 ml
ATC code N01AH01

ANESTHETICS, GENERAL

This medicine is used:
- as a narcotic analgesic supplement in general or regional anaesthesia;
- in combination with a neuroleptic (e.g. droperidol) in the technique of neuroleptanalgesia;
- for the induction of anaesthesia, and as an adjuvant in the maintenance of general and regional anaesthesia;
- as an anaesthetic agent with oxygen in high-risk patients undergoing surgery.

Fentanyl nasal spray* (generic of PecFent®)
Strength 50 µg/dose, 200 µg/dose
Volume 2.9 ml
ATC code N02AB03

ANALGESIC, OPIOID

*under development

Fentanyl sublingual tablets* (generic of Abstral®)
Strength 200 μg, 300 μg, 400 μg, 600 μg, 800 μg
Volume -
ATC code N02AB03

ANALGESICS, OPIOIDS

*under development

Hydromorphone hydrochloride injection (generic of Palladone®)
Strength 2 mg/ml, 10 mg/ml, 20 mg/ml, 50 mg/ml
Volume 1 ml
ATC code N02AA03

ANALGESIC, OPIOID

This medicine is used for the treatment of severe pain.

Metamizole sodium injection (generic of Novalgin®)
Strength 500 mg/ml
Volume 2 ml, 5 ml
ATC code N02BB02

ANALGESICS, OTHER ANALGESICS AND ANTIPYRETICS

This medicine is used for treatment of severe acute or chronic pain. Fever not responding to other treatment.

Midazolam injection (generic of Dormicum®)
Strength 5 mg/ml
Volume 1 ml, 3 ml
ATC code N05CD08

HYPNOTICS AND SEDATIVES

This medicine is a short-acting hypnotic with the following indications for use:

Adults
• CONSCIOUS SEDATION with or without local anaesthesia before or during diagnostic or therapeutic procedures
• ANAESTHESIA
- Premedication before the induction of anaesthesia
- Induction of anaesthesia
- As a sedative component in maintenance of anaesthesia
• SEDATION IN THE INTENSIVE CARE UNIT

Children
• CONSCIOUS SEDATION with or without local anaesthesia before or during diagnostic or therapeutic procedures
• ANAESTHESIA
- Premedication before the induction of anaesthesia
• SEDATION IN THE INTENSIVE CARE UNIT

Morphine hydrochloride injection
Strength 10 mg/ml, 20 mg/ml
Volume 1 ml, 5 ml, 10 ml
ATC code N02AA01

ANALGESIC, OPIOID

This medicine is used for treatment of severe pain conditions which can be adequately managed only with opioid analgesics. Myocardial infarction, acute pulmonary oedema.

Morphine sulfate injection (w/o preservatives)
Strength 2 mg/ml, 5 mg/ml, 10 mg/ml, 15 mg/ml, 30 mg/ml
Volume 1 ml
ATC code N02AA01

ANALGESIC, OPIOID

This medicine is used for the relief of severe pain. It is also used to treat breathlessness caused by fluid in the lungs and as a pre-medication before operations.

Nefopam injection* (generic of Acupan®)
Strength 10 mg/ml
Volume 2 ml
ATC code N02BG06

ANALGESICS, OTHER

* under development

Neostigmine metilsulfate injection
Strength 0.5 mg/ml
Volume 1 ml
ATC code N07AA01

OTHER NERVOUS SYSTEM DRUGS, PARASYMPATHOMIMETICS

This medicine is indicated for:
- myasthenia gravis.
- reversal of the neuromuscular blockade produced by non-depolarising neuromuscular blockers.
- paralytic ileus.
- management of postoperative urinary retention.

Oxycodone hydrochloride injection/infusions (generic of Oxycontin®)
Strength 10 mg/ml, 50 mg/ml
Volume 1 ml, 2 ml
ATC code N02AA05

ANALGESIC, OPIOID

This medicine is used for:
- the treatment of moderate to severe pain in patients with cancer and postoperative pain;
- the treatment of severe pain requiring the use of a strong opioid.

Piracetam injection
Strength 200 mg/ml
Volume 5 ml, 10 ml
ATC code N06BX03

PSYCHOANALEPTICS, PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS

This medicine is used for treatment of dizziness of central origin and its related symptoms.
Treatment of myoclonus caused by cerebral cortex damage in combination with other anti-myoclonic medicines.

Piritramide injection* (generic of Dipidolor®)
Strength 7.5 mg/ml, 10 mg/ml
Volume 1 ml, 2 ml, 6 ml
ATC code N02AC03

ANALGESICS, OPIOIDS

* under development

Remifentanil powder for injection* (generic of Ultiva®)
Volume 1 mg, 2 mg, 5 mg
ATC code N01AH06

ANESTHETICS, GENERAL

*under development

Ropivacaine injection* (generic of Naropin®)
Strength 2 mg/ml, 5 mg/ml, 7.5 mg/ml, 10 mg/ml
Volume 10 ml, 20 ml, 100 ml, 200 ml
ATC code N01BB09

ANESTHETICS, LOCAL

* under development

Sodium oxybate injection
Strength 200 mg/ml
Volume 10 ml
ATC code N01AX11

ANESTHETICS, GENERAL

This medicine is used:
- in general and pediatric surgery for the induction of anaesthesia and basal narcosis (especially in patients with hypoxia, respiratory insufficiency or heart disease);
- as narcosis for surgery in elderly patients with hypotension and hypovolaemia;
- for anesthesia in various diagnostic procedures for all groups of ages.

Sufentanil injection (generic of Sufenta®)*
Strength 0.005 mg/ml, 0.05 mg/ml
Volume 2 ml, 5 ml, 10 ml
ATC code N01AH03

ANESTHETICS, GENERAL

*under development

Tramadol hydrochloride injection (generic of Tramal®)
Strength 50 mg/ml
Volume 1 ml, 2 ml
ATC code N02AX02

ANALGESIC, OPIOID

This medicine is used for treatment of moderate to severe pain.

Trimeperidine hydrochloride injection
Strength 20 mg/ml
Volume 1 ml
ATC code N02AX

ANALGESIC, OPIOID

This medicine is used relieve severe pain in the case of injuries, fractures of bones, burns, miocardial infarction, acute pancreatitis, renal, biliary and intestinal colic, in the case of malignant tumour, as well as after surgery.
To relieve labour pain and to accelerate labour in the case of cervical dysfunction, when epidural anaesthesia is impossible and childbirth is predictable not earlier than after two hours.
For premedication before surgery.